My configuration is:
Videocard GeForce GTX 1060 G1 Gaming 6GB (x4)
Risers PCI-E to 1x version 006 (x4)
HDD WD 1Tb blue (x1)
RAM GoodRam 4gb (x2)
CPU Amd FX 8300 with cooler Zalman Performa 10x (x1)
Motherboard ASUS M5A97 R.2.0 (x1)
Power Block CHIEFTEC 1000W (APS-1000CB) (x1)
Operating System Windows 10 x64 Pro
Miner EWBF 0.3.4b + my own autorun script
For me working fine, speed 1300 Sols/s.
Month profit near 200$ (electricity cost 0.05$/Kwh)
It is my computer for work and zcash farm both.
Maybe soon I will update my motherboard and take more videocards.
Or what do you want to know?
Just buy this computer, install soft, press 1 button - profit 
It is really simple!