I am new newbie in Zcash. Is it worthwhile to mine with Windows 10 PC?
Hey, it's worth it. It mainly depends on your hashing power, which is vastly independent from the OS you are using. Mining with CPU only isn't cost-effective and generally speaking you're better off with a recent graphic card and a powerful GPU if you want to achieve some results. I've posted an article about that in the Education section recently.
GPU mining is profitable but dependant on what you pay for electricity and the GPU. I am toying with the idea of using previous generation AMD GPUs for ZEC mining.