Yes, that is exactly what you use. In your Claymore folder you should see a file "Start.bat". Right click on that and click edit. Erase everything in there and paste the following. When done, save and double click on it to start mining.
setx GPU_MAX_ALLOC_PERCENT 100
setx GPU_SINGLE_ALLOC_PERCENT 100
ZecMiner64.exe -zpool us1-zcash.flypool.org:3333 -zwal yourpoloniexaddress.%hostname% -zpsw x
Change yourpoloniexaddress to your address of course and if you are in a region besides the US you might want to change the prefix on the pool address "US1" to something else, maybe EU1.
You can just manually put a miner name too instead of the hostname part, I use this as I have many rigs and it makes naming them on the pools easier.