Video Cards (NVidia and AMD) feasible to be OPTIMIZED?

Good afternoon,

Because I am beginner in mining, I am interested to know if I want to multi-mining with optimized BIOS and GPU’s (I will use in 1 rig both AMD and NVidia GPU’s) will affect (in better way) performance for all coins ?
What coin I must considerate as reference in GPU’s optimization ? (for ex. Bitcoin, ZCASH, Ethereum, and so on …)
Somebody already try to mining in this way ?

I waiting with higher interest your feedback with remarks and suggestion.
Thank you in advance to all community support and for understanding.
Keep in touch.

Kind regards.

P.S. I will use Ubuntu (Linux) as operating system